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FLASH GENE
Symbol GSDMB contributors: SGE - updated : 04-06-2007
HGNC name gasdermin B
HGNC id 23690
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1578 - 403 - Suzuki
- - 1646 - 394 - Suzuki
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon highly
 liver    
Endocrinethyroid   highly
Lymphoid/Immunethymus   highly
Nervousbrain    
Reproductivemale systemprostate   
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
cell lineage expressed in proliferating cells
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory , protooncogene
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm
basic FUNCTION
  • involved in the regulation of cell growth and differentiation in the skin and/or hair follicle epithelium, as well as the epithelium of the gastrointestinal tract
  • may be an oncogene (Saeki, 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS