Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --over
|  
|
lung cancer | constitutional
|  
|  
| --low
|  
|
during DNA damage | tumoral
|  
|  
| --over
|  
|
frequently in malignant peripheral nerve sheath tumor cells | constitutional
|  
|  
| --low
|  
|
causes a hyper-stabilization of spindle MT, a loss of inter-kinetochore tension, and a defect in chromosome congression, leading to unaligned chromosomes at metaphase | |