Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | NXNL1 | contributors: mct - updated : 11-12-2015 |
HGNC name | nucleoredoxin-like 1 |
HGNC id | 25179 |
|
RNA |
TRANSCRIPTS | type | messenger |
---|
EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||
organ(s) |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
HOMOLOGY |
intraspecies | paralog to NXNL2 |
Homologene |
FAMILY |
CATEGORY | transport carrier |
SUBCELLULAR LOCALIZATION | extracellular |
plasma membrane | |
intracellular | |
intracellular,cytoplasm,organelle,mitochondria,outer | |
intracellular,cytoplasm,organelle,membrane | |
intracellular,nucleus |
basic FUNCTION | |
| |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | electron transport |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
| |
|
cell & other |
REGULATION |
induced by | at high levels in lens epithelial cells exposed to H(2)O(2)-induced oxidative stress |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
| |
|
|
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ANIMAL & CELL MODELS |
in the rd1 mouse, a model of RP, the expression by rods of the trophic factor NXNL1 is lost through their degeneration, but the reduction in its expression by bipolar cells results from a downregulation of its expression |