basic FUNCTION
| tandem tudor domain protein that is expressed in male germ cells and localizes to chromatoid bodies |
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essential for haploid spermatid development and with TDRD6, are key biogenesis processes of chromatoid bodies |
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TDRD7 and TDRD6 constitute a spermiogenic class of tudor family genes, which function in a sequential and nonredundant manner |
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TDRD7 and TDRD6, play key roles in the early ribonucleoprotein remodeling and later structural maintenance, respectively |
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essential for early spermatid differentiation and is a master regulator of the biogenesis of chromatoid bodies |
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essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis |
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TDRD5 and TDRD7, play key roles in facilitating the function of PIWIs by acting as scaffolds |
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TDRD5-TDRD7 are required for spermiogenesis |
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TDRD5, TDRD7, RNF17 proteins play distinct roles during male germ cell development |
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TDRD7 plays an essential role in the maturation of autophagosomes |
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