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FLASH GENE

Symbol

PGM2

contributors: mct - updated : 17-12-2015

HGNC name	phosphoglucomutase 2
HGNC id	8906

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 14 - 3192 - 612 - Maliekal (2007)

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive esophagus       highly Lymphoid/Immune spleen       highly   thymus       highly Respiratory lung       highly Urinary bladder       highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

TASHNP motif common to members of the -D-phosphohexomutase family

HOMOLOGY

Homologene

FAMILY

phosphohexose mutase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic

basic FUNCTION	acts mainly as a phosphopentomutase, also catalyzes the synthesis of Glc-1,6-P2 (Veiga-da-Cunha 2008)
	participating in both the breakdown and synthesis of glucose
	having phosphopentomutase activity

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

carbohydrate

signaling

a component

INTERACTION

DNA

RNA

small molecule	metal binding,
	binds 1 magnesium ion per subunit

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS