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FLASH GENE
Symbol NUDT16L1 contributors: mct - updated : 16-05-2017
HGNC name nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
HGNC id 28154
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 1437 - 192 - 2008 18820299
3 - 1367 - 211 - 2008 18820299
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Reproductivemale systemprostate   
Respiratorylung    
cells
SystemCellPubmedSpeciesStageRna symbol
Nervousoptic nerve
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a Nudix (Nudt) motif
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY adhesion , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • is inactive for RNA decapping but retains RNA-binding activity
  • potential molecular function of NUDT16L1 in the regulation of cell signaling via binding to SDC4
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • with paxillin (PXN ) and SDC4, syndecan 4(for the cooperative signaling in the assembly of focal adhesion and actin stress fibers)
  • co-localized with SDC4 cytoplasmic domain in focal contacts, interacts with various cell adhesion adaptor proteins to control cell signaling
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS