basic FUNCTION
| potential role in regulation of cell cycle |
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protects against apoptosis, maybe by enhancing AKT kinase activation |
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potential role in promoting lymphoid tumor development |
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accelerates TP53 degradation by means of the ubiquitin-dependent proteolysis |
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loss of TP53, with its overexpression synergistically promote chromosome instability and tumorigenicity |
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implicated in the interaction with the cap complex of the mRNA, through an RNA binding domain, named PUA |
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LGTN and MCTS1/DENR promote release of tRNA and mRNA from recycled 40S subunits |
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roles for Ligatin and the related interacting proteins MCTS1 and DENR in ribosome recycling and initiation, two linked stages of translation |