basic FUNCTION
| transcriptional repressor activity |
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negative regulation of transcription |
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is a novel deadenylase expressed specifically in cell types which share regulatory mechanisms required for multipotency maintenance |
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PNLDC1 shows limited conservation compared to PARN and represents an evolutionary related but distinct group of enzymes |
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is a novel deadenylase expressed specifically in cell types which share regulatory mechanisms required for multipotency maintenance, but it could be involved both in posttranscriptional regulation through deadenylation and genome surveillance during early development |
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is likely a mammalian piwi-interacting RNA biogenesis factor that protects the germline genome and ensures normal sperm production |