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FLASH GENE
Symbol SYT15 contributors: - updated : 27-10-2004
HGNC name synaptotagmin XV
HGNC id 17167
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 4862 47 421 - Fukuda
isoform a contains two C2 domains
- - 1536 - 390 - Fukuda
variant b contains an alternate 3' sequence (lacks exon 8), resulting in isoform b which lacks a C2 domain
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Nervousbrainhindbraincerebellum  
 braindiencephalonthalamus  
Reproductivemale systemtestis  predominantly
Respiratorylung   predominantly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N-terminal transmembrane domain
  • putative fatty-acylation sites
  • two C-terminal tandem C2 domains
  • HOMOLOGY
    interspecies homolog to murine Syt15
    homolog to rattus sytXV
    Homologene
    FAMILY synaptotagmin family
    CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    text type III transmembrane protein
    basic FUNCTION may be involved in the trafficking and exocytosis of secretory vesicles in non neuronal tissues
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS exocytosis transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule other,
    phospholipid binding in a Ca2+ independent manner
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS