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FLASH GENE
Symbol POLR2F contributors: - updated : 02-09-2006
HGNC name polymerase (RNA) II (DNA directed) polypeptide F
HGNC id 9193
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveintestinesmall intestine  highly
Nervousbrain   highly
Skin/Tegumentskin   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY eukaryotic RPB6 RNA polymerase subunit family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • sixth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA, that is also shared by the other two DNA-directed RNA polymerases
  • catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
  • CELLULAR PROCESS nucleotide, replication
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS