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FLASH GENE
Symbol ZNF2 contributors: - updated : 25-07-2006
HGNC name zinc finger protein 2 (A1-5)
HGNC id 12991
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Endocrinepancreas    
Lymphoid/Immunespleen   highly
Nervousbrain    
Reproductivefemale systemuteruscervix highly
 male systemtestis  predominantly
Respiratoryrespiratory tracttrachea  highly
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • zinc finger protein containing a potent N terminal transcriptional repression domain
  • the KRAB/FPB module
  • a C terminal zinc finger domain composed of 19 Krüppel-type C2H2 finger motifs
  • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to Drosophila CG18555
    Homologene
    FAMILY zinc finger protein family, C2H2 type, Krüppel-like, KR
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION potential transcriptional repressor, may be involved in transcriptional regulation
    CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    zinc Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS