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FLASH GENE
Symbol FCRLA contributors: np - updated : 15-06-2006
HGNC name Fc receptor-like A
HGNC id 18504
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 2357 - 376 - -
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunespleen    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneB cell
Skin/Tegumentmelanocyte
cell lineage
cell lines
fluid/secretion lymph
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a signal peptide
  • a hydrophilic peptide
  • two IgSF domains
  • a proline-rich region
  • a leucine-rich region
  • an endoplasmic reticulum retention signal
  • conjugated GlycoP
    mono polymer monomer , dimer
    HOMOLOGY
    interspecies homolog to murine Fcrla (71.9pc)
    Homologene
    FAMILY Fc receptor family
    CATEGORY receptor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • implicated in B-cell development and lymphomagenesis
  • may be having a unique role in B-cell differentiation
  • may function in melanocytes and melanoma and may be useful for development of diagnostic methods for various pigment disorders and immunotherapy of melanoma
  • CELLULAR PROCESS cell life, differentiation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS