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FLASH GENE
Symbol ADNP2 contributors: mct - updated : 16-10-2015
HGNC name ADNP homeobox 2
HGNC id 23803
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 5401 122.8 1131 - 2008 1817947
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
cells
SystemCellPubmedSpeciesStageRna symbol
Nervousoligodendrocyte Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text photoreceptor cells in development
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , dimer
HOMOLOGY
intraspecies homolog to ADNP
Homologene
FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    text soma and axons of photoreceptor cells of compound eyes and ocelli.
    basic FUNCTION
  • may be functioning as a calcium-sequestering "sponge" to regulate the amount of free cytoplasmic calcium
  • may have an important function in brain by playing a role in cellular survival pathways
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • imbalance in ADNP/ADNP2 expression in the brain may impact disease progression in schizophrenia
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS