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FLASH GENE
Symbol SCFD1 contributors: mlc/npt - updated : 12-12-2007
HGNC name sec1 family domain containing 1
HGNC id 20726
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
25 - 2156 - 642 - Matsuo, Beausoleil (2004)
24 - 2085 - 575 - Matsuo, Beausoleil (2004)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
Endocrineneuroendocrinepituitary  highly
Nervousbrain    
Reproductivefemale systemuterus  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to rattus Ra410
homolog to murine Scfd1
Homologene
FAMILY
  • STXBP/UNC-18/SEC1 family
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • may be involved in vesicular transport between the endoplasmic reticulum and the Golgi
  • having a function intimately associated with syntaxin binding, perhaps promoting a later step in SNARE complex formation or function
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • STX5
  • interacting with the COG tethering complex via the COG4 subunit, interaction that is required for Golgi SNARE pairing (Laufman 2009)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS