basic FUNCTION
| intracellular messenger of GPCR signaling in energy homeostasis |
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may be involved in the hypothalamic regulation of body weight |
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lacks phosphatidylserine-binding activity, but is capable of associating with PtdIns(4,5)P2 on the inner leaflet of the plasma membrane through its highly conserved C-terminal domain |
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Tubby and TULP1, but not other family members, enhanced the uptake of membrane vesicles by retinal pigment epithelium (RPE) cells in synergy |
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potential role for TUB in insulin signalling and fuel homeostasis in adipocytes |
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tubby and TULP1 are new type of MERTK ligands to facilitate phagocytosis |
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tubby and TULP1 have potentially a critical function as phagocytosis ligands in the maintenance of retinal homeostasis |
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plays a critical role in trafficking select GPCRs to the cilia |
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plays important roles in the maintenance and function of neuronal cells |