basic FUNCTION
| pathogen component (pathogen recognition and activation of innate immunity), mediating the production of cytokines |
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play a major role in initiating innate immune responses against microbes (Barreiro 2009) |
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recognize specific pathogen-associated molecular patterns and to alarm immunocompetent cells to trigger an immune response (Muzio 2009) |
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playing a potential role in modulating Chronic Lymphocytic Leukaemia cell response in the context of specific antigen recognition (Muzio 2009) |
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TLR1, TLR2, TLR6, and TLR10, mediates immune responses to a variety of microbial cell wall components including lipoproteins and glycolipids |