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FLASH GENE
Symbol KRT6C contributors: npt/mct - updated : 20/10/2008
HGNC name keratin 6C
HGNC id 20406
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 2345 60 564 - Schweizer (2006)
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
digestiveesophagus    
Digestivepharynx   highly
Respiratoryrespiratory tractlarynx  highly
Skin/Tegumentskin appendageshairfollicle  
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialabsorptive excretorydigestive epithelium  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer heteromer , dimer
HOMOLOGY
interspecies homolog to murine Krt2-6a
homolog to chimpanzee LOC451918
Homologene
FAMILY
  • intermediate filament family
  • type II keratin family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,intermed filament
    text expressed with family members KRT16 and/or KRT17
    basic FUNCTION
  • neutral protein arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • heterodimer of a type I (acidic) and a type II (neutral to basic) keratin
  • dimerizing with KRT16 and/or KRT17
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to KRT16, KRT17
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS