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FLASH GENE
Symbol TGM7 contributors: mct - updated : 04-06-2019
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
13 - 2312 - 710 - 2001 11390390
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularsmoothvessel   Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Cardiovascularendothelial cell Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • conserved Cys-His-Asp triad
  • one calcium binding domain
  • HOMOLOGY
    Homologene
    FAMILY transglutaminase family
    CATEGORY
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • catalyzing the cross-linking of proteins and the conjugation of polyamines to proteins
  • TGM2 (and possibly also TGM3, TGM7) gained vital functions which have not been fully revealed, yet
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral fusion      
    UBAP1-TGM7, was unique to clear cell (CC) epithelial ovarian cancer (EOC) tumors
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS