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FLASH GENE
Symbol TGIF2LY contributors: SGE/npt - updated : 25-06-2010
HGNC name TGFB-induced factor homeobox 2-like, Y-linked
HGNC id 18569
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
2 - 880 - 185 - Blanco-Arias (2002)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  specific
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one homeobox DNA-binding domain
  • HOMOLOGY
    Homologene
    FAMILY
  • TALE/TGIF homeobox family of transcription factors
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may be acting as a regulator of TGIF2LX
  • may have a transcriptional role in testis
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
  • binding
  • RNA
    small molecule
    protein
  • interacting with CTBP, MADH2, MADH3, HDAC1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
  • association of TGIF2LY/X expression with the progression of prostate cancer (Ousati-Ashtiani 2009)
  • Marker
    Therapy target
    ANIMAL & CELL MODELS