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FLASH GENE
Symbol NUDT12 contributors: - updated : 13-11-2006
HGNC name nudix (nucleoside diphosphate linked moiety X)-type motif 12
HGNC id 18826
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Skin/Tegumentskin    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an ankyrin repeat in its N-terminal half
  • a consensus Nudix (Nudt) motif
  • an NADH diphosphatase-like sequence in its C-terminal half
  • HOMOLOGY
    interspecies homolog to murine Nudt12
    Homologene
    FAMILY
  • NUDIX family of hydrolases
  • NudC subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,peroxisome
    basic FUNCTION
  • having hydrolase activity
  • may act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
  • magnesium
  • manganese
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS