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FLASH GENE
Symbol MAN1C1 contributors: npt/ - updated : 04-09-2004
HGNC name mannosidase, alpha, class 1C, member 1
HGNC id 19080
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
14 - 3201 70.8 630 - Hosokawa (2007)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveintestinelarge intestinecolon  
 liver    
Lymphoid/Immunespleen    
 thymus    
Nervousbrain    
Reproductivefemale systemovary   
 male systemprostate   
 male systemtestis   
Urinarykidney    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a cytoplasmic domain
  • a transmembrane domain
  • a luminal domain
  • two N glycosylation sites
  • a proline rich stem region
  • the catalytic site
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • glycosyl hydrolase 47 family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • involved in the hydrolysis of the terminal 1,2-linked alpha-D- mannose residues in the
  • oligo-mannose oligosaccharide Man(9)(GlcNAc)(2)
  • involved in the maturation of Asn-linked oligosaccharides
  • CELLULAR PROCESS protein, post translation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    N-glycosylation
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS