protein
| binding to IL22, Stat3, Jak1, CRF2-4, IL22RA, IL22RA1 and IL-20RB |
|
IL22 secreted by decidual stromal cells (DSCs) and decidual natural killer (dNK) cells might promote the survival of trophoblasts and participate in the maintenance of pregnancy by binding to the IL22RA1 |
|
increased expression of IL22RA1 promotes keratinocyte proliferation and pro-inflammatory cytokine production during UVB-induced skin inflammation, suggesting that UVB facilitates skin inflammation by increasing the responsiveness of keratinocytes to IL22 |