basic FUNCTION
| inducing apoptosis |
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myosin-light chain kinase |
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transcriptional co-activator of the AR (interaction of ZIP kinase with AR seems to be mediated in part by apoptosis antagonizing transcription factor and in part by direct binding) |
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binding partner of activating transcription factor 4 (ATF4), a member of the activating transcription factor/cyclic AMP-responsive element-binding family of transcription factor proteins |
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plays a crucial role in androgen receptor-mediated transcription |
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implicated in cell death and transcriptional regulation |
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tumor suppresser gene, playing an important role in gastric cancer development through its pro-apoptotic function |
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may act as a cardiac regulatory light chain kinase and thereby affect contractility |
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Ca2+-independent kinase with various substrates participating in diverse processes, ranging from promotion of apoptosis, to attenuation of inflammatory signaling, to regulation of contraction in smooth muscle |
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with PPP1R14A, participate in the regulation of PRKCA and PRKCE on vascular calcium sensitivity after hemorrhagic shock |
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Ca(2+)-independent protein kinase that promotes myosin phosphorylation in both smooth muscle and non-muscle cells |
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tumor suppressor in which loss-of-function mutations promote increased cell survival, proliferation, cellular aggregation, and increased resistance to chemotherapy |
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may serve as a transcriptional regulator of canonical Wnt/beta-catenin signaling through interaction with NLK/TCF4 |
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controls proliferation, migration, invasion, soft& |
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8209;agar colony formation and tumor growth through activation of ERK/MYC signaling in A549 cells |