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FLASH GENE
Symbol ABLIM2 contributors: - updated : 26-09-2006
HGNC name actin binding LIM protein family, member 2
HGNC id 19195
RNA
TRANSCRIPTS type messenger
text two potential isoforms
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2589 - 611 - Klimov
20 exons
- - 2472 - 572 - Klimov
18 exons
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Cardiovascularheart   moderately
Endocrinepancreas    
Nervousbrain   highly
Respiratorylung    
Urinarykidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four N terminal cysteine-rich LIM/double zinc finger motifs
  • a C terminal end homolog to actin-bundling domain of erythrocyte cytoskeleton (dematin like domain /villin headpiece domain (VHP)
  • HOMOLOGY
    intraspecies homolog to ABLIM1
    Homologene
    FAMILY LIM protein family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton
    intracellular,nucleus
    basic FUNCTION
  • involved in cytoskeleton organization and biogenesis
  • playing a necessary role for the normal functioning of neurons
  • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS nervous system
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    zinc, Zn2+
    protein binding to actin and bundling actin filaments
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS