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FLASH GENE
Symbol SLC15A3 contributors: np/ - updated : 14-04-2010
HGNC name solute carrier family 15, member 3
HGNC id 18068
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 2134 - 581 - 2001 11336635
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   lowly Homo sapiens
Lymphoid/Immunespleen   highly Homo sapiens
Reproductivefemale systemplacenta  highly Homo sapiens
Respiratorylung   highly Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES fibrous
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine C.AMP inducible gene 1
intraspecies homolog to PHT1
Homologene
FAMILY
  • PTR2/POT transporter family
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in the protein catabolic pathway in the lymphatic system
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    by hypermethylation in head and neck tumors
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS