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FLASH GENE
Symbol NT5C3A contributors: mct/npt - updated : 07-07-2014
HGNC name 5'-nucleotidase, cytosolic IIIA
HGNC id 17820
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 1727 - 336 reticulocyte 2009 19623099
an additional sequence overlapping exons 2 and 3
10 - 1782 33 297 - 2009 19623099
10 - 1846 34 297 - 2009 19623099
11 - 1932 - 285 - 2009 19623099
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   moderately
Digestiveliver   moderately
Lymphoid/Immunelymph node   highly
Nervousbrain   moderately
Respiratorylung   moderately
Urinarybladder   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
Muscularstriatumskeletal highly
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticerythrocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
  • pyrimidine 5'-nucleotidase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • catalyzing the dephosphorylation of pyrimidine nucleoside monophosphate
  • transferring phophate groups between pyrimidine monophosphates and varioux pririmidine nucleosides
  • is responsible for selective degradation of pyrimidine 5prime-monoribonucleotides during maturation of reticulocytes to erythrocytes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism purine/pyrimidine
    signaling
    pyrimidine metabolism
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Mg2+ dependent
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) P5N1D
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS