basic FUNCTION
| mediating calcium dependent bidirectional movement between membrane bilayers in injured,activated or apoptotic cells |
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downstream effector of PRKCD in the mitochondria |
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may play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system |
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playing an analogous role in signaling and in the cellular response to insulin |
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novel regulator of cardiolipin de novo biosynthesis and its resynthesis |
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transports CL (cardiolipin) from the inner to the outer mitochondrial membrane |
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plays an important role in regulation of mitochondrial morphology, respiratory function, and apoptotic responses |
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playing a role in adipose lipid metabolism |
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facilitate the translocation of aminophospholipids from the inner to the exterior leaf of the cell membrane |
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its expression facilitates changes in mitochondrial membrane lipids that promote the release of apoptogenic factors and consequent full activation and processing of the caspase-9 and effector caspase-3 |