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FLASH GENE
Symbol CDKL2 contributors: - updated : 19-10-2004
HGNC name cyclin-dependent kinase-like 2 (CDC2-related kinase)
HGNC id 1782
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainforebraincerebral lobefrontal 
Reproductivemale systemtestis   
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
MAP kinase dual phosphorylation motif (Thr-Asp-Tyr)
HOMOLOGY
interspecies homolog to rattus Kkialre,serine/threonine/kinase
Homologene
FAMILY CDC2-related serine/threonine protein kinases family
CATEGORY enzyme , receptor membrane serine/threonine
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
intracellular,nucleus
basic FUNCTION
  • playing a key role in the control of the eukaryotic cell cycle.
  • playing a role in learning and memory
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text sex differentiation
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by treatement of cell with EGF
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS