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FLASH GENE
Symbol MUC13 contributors: npt - updated : 20-09-2006
HGNC name mucin 13, cell surface associated
HGNC id 7511
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
12 - 2961 54.6 511 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestine  highly
 intestinesmall intestine  moderately
 stomach   moderately
Reproductivemale systemprostate  moderately
Respiratorylung   moderately
 respiratory tracttrachea  highly
Urinarykidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularexocrine 
cells
SystemCellPubmedSpeciesStageRna symbol
Digestivegoblet
Respiratorygoblet cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal mucin repeat domain
  • three epidermal growth factor-like sequences
  • a SEA module
  • a transmembrane domain
  • a cytoplasmic tail
  • conjugated GlycoP
    mono polymer homomer , dimer
    HOMOLOGY
    interspecies homolog to mucine Ly64
    Homologene
    FAMILY
    CATEGORY immunity/defense , antigen
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in barrier function in epithelial tissues
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • beta subunit produced by cleavage of MUC13 and containing the cytoplasmic tail undergoes homodimerization
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS