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FLASH GENE
Symbol BCAS3 contributors: - updated : 26-05-2006
HGNC name breast carcinoma amplified sequence 3
HGNC id 14347
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
25 - 3626 - 928 - -
24 - 3581 - 913 - -
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularvessel    
Digestiveliver    
 mouthtongue  highly
Reproductivefemale systembreastmammary gland highly
 male systemtestis  highly
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose  highly
Epithelialsecretoryglandular  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, fetal
Text kidney, stem cells
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY protooncogene
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • involved in the pathogenesis of breast cancer
  • important role for MTA1-BCAS3 pathway in promoting cancerous phenotypes in breast tumor cells
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • target of MTA1
  • cell & other
    REGULATION
    Other regulated by MTA1
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   amplification    
    in breast carcinoma
    tumoral fusion      
    with BCAS4 in breast cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS