basic FUNCTION
| dephosphorylating exogenous bioactive glycerolipids and sphingolipids |
|
catalyzing the conversion of phosphatidic acid (PA) to diacylglycerol (DG) |
|
acting as a pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system |
|
being the major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA |
|
may control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation |
|
having little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P) |
|
involved in the activation of protein kinase C |