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FLASH GENE

Symbol

ERMAP

contributors: mlc/np - updated : 10-11-2007

HGNC name	erythroblast membrane-associated protein (Scianna blood group)
HGNC id	15743

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

text	Variants 1 and 2 encode the same protein

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 3485 52 475 - Gregory (2006) variant 2 - - 3381 52 475 - Gregory (2006)

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine adrenal gland       highly   neuroendocrine pituitary     highly Respiratory respiratory tract trachea     highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic bone marrow

cell lineage	erythroid cells
cell lines
fluid/secretion

at STAGE

physiological period

fetal

Text

liver

PROTEIN

PHYSICAL PROPERTIES		Hydrophobic
STRUCTURE

motifs/domains	transmembrane domain
	one extracellular immunoglobulin Fold (IGV)
	three B30-2 motif in the cytoplasmic region

HOMOLOGY

interspecies

homolog to murine Ermap

Homologene

FAMILY

B30-2 domain protein family

CATEGORY

adhesion , receptor membrane

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION	involved in normal development of red blood cells in adult and fetus
	expressing the antigens of the Scianna blood group including Rd

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS