protein
| direct interaction with the basolateral sorting signal of APP/APLPs (functional link between APP/APLPs transport and their processing) |
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binds RNA and has numerous domain-specific interactions with mRNA decapping factors |
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SLC36A1 has a relatively low affinity for its substrates, which include zwitterionic amino and imino acids, heterocyclic amino acids and amino acid-based drugs |
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is an essential mediator of AA-dependent MTOR activation |
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5-aminolevulinic acid (ALA) appears to be transported into erythroid cells mainly by SLC36A1 and is utilized to generate heme |
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SLC36A1 can likely negatively regulate MTOR by controlling the cellular nutrient signal level |
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SLC38A9 interacted with SLC36A1 and they enhanced each other's expression levels and locations on the lysosomal surface |