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FLASH GENE
Symbol GNB1L contributors: mct - updated : 25-03-2008
HGNC name guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HGNC id 4397
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 1537 35 327 - Williams (2008)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveliver   highly
Endocrinepancreas    
 thyroid   highly
Hearing/Equilibriumear   highly
Lymphoid/Immunethymus    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Lymphoid    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal six putative WD40 repeat (44 to 60AA containing GLY-HIS)
  • C terminal WD (TRP-ASP) dipeptide and a conserved core sequence
  • HOMOLOGY
    interspecies homolog to murine gub1l
    Homologene
    FAMILY WD40 repeat family
    CATEGORY signaling , receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to schizophrenia
    Variant & Polymorphism SNP increasing the risk of schizophrenia
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS