basic FUNCTION
| involved in negative regulation of DNA regulation |
|
playing a role in negative regulation of cell cycle and growth |
|
involved in regulation of signal transduction |
|
represses the cyclin B1-CDK1 phosphorylation activity |
|
could serve a normal function in modulating cell-cycle progression at the G(2)/M stage |
|
is essential for the formation of canonical Cajal bodies (CBs), histone transcription, and cell viability |
|
serves a biological role in maintaining the G1 checkpoint under stress condition (pMID: 21738728) |
|
may not simply regulate nucleotide homeostasis, but may have broader functionality, including control of Cajal Bodies (CBs), assembly and disassembly in the nucleus of human cells |
|
nucleosome assembly protein |
|
contributes to cognitive variability through regulating the expression of GRIN2A and GRIN2B |
|
REST and TSPYL2 are regulators of TGFB1 signaling and cell-cycle arrest induced by TGFB1 requires both REST and TSPYL2 |