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FLASH GENE
Symbol IGSF5 contributors: mct/npt - updated : 03-07-2008
HGNC name immunoglobulin superfamily, member 5
HGNC id 5952
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 2066 - 407 - Ota (2004)
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemplacenta   
Urinarykidney    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticprogenitor cell
Reproductivegerm cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an intracellular Ig-like domain with potential N glycosylation site
  • a transmembrane segment
  • a cytoplasmic tail
  • two PDZ domains
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • immunoglobulin superfamily
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane,junction,tight
    basic FUNCTION
  • implicated in the regulation of paracellular permeability and the signalings of hepatocyte growth factor
  • implicated in the reorganization of cell junctions
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with MAGI1
  • interacting with LNX1(directly binds the second PDZ domain of LNX1 through its carboxyl terminus)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS