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FLASH GENE
Symbol RABGGTB contributors: mct/npt - updated : 31-03-2009
HGNC name Rab geranylgeranyltransferase, beta subunit
HGNC id 9796
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 1526 36 331 - Olsen (2006)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland   highly
Hearing/Equilibriumear   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer dimer
HOMOLOGY
interspecies ortholog to rattus Rabggtb
ortholog to murine Mbeta,Rabggtb
ortholog to yeast S.pombe spbeta
ortholog to C.elegans
Homologene
FAMILY
  • protein prenyltransferase subunit beta family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • regulator of vesicular transport steps in endocytic and secretory pathways
  • having a post-transcriptional regulation of its gene expression (Chinpaisal 1997)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • beta subunit forming a dimer with alpha subunit
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interaction with CHODL (Claessens 2008)
  • cell & other
    REGULATION
    activated by Rab escort proteins (REP1,CHML)
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS