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FLASH GENE
Symbol SSR2 contributors: - updated : 18-01-2006
HGNC name signal sequence receptor, beta (translocon-associated protein beta)
HGNC id 11324
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunethymus   highly
Reproductivefemale systemovary  highly
 male systemprostate  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
glycosylated
mono polymer heteromer , tetramer
HOMOLOGY
Homologene
FAMILY TRAP-beta family
CATEGORY receptor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,matrix
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
basic FUNCTION
  • signal sequence receptor, beta, involved in protein translocation process
  • part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • glycosylated membrane protein constituent of endoplasmic reticulum
  • heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS