basic FUNCTION
| playing a regulatory role in the development of the ventral forebrain |
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may be playing a role in craniofacial patterning and morphogenesis |
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playing a critical role in enamel formation and dentin formation |
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essential for hair morphogenesis, differentiation and cycling programs |
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necessary for normal placentation |
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has a regulatory role in villous cytotrophoblast (VCT) differentiation |
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regulated the expression of inner root sheath (IRS) keratins |
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is essential for osteoblast differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression |
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orchestrates the expression of multiple regulators of trophoblast differentiation and expression of these regulatory genes is abnormal in fetal growth restriction (FGR) |
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is a central attenuator of adult bone mass in the appendicular skeleton |
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transcription factor, critical for the development of hair follicle and hair formation and regeneration |
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DLX3 is a novel target of ESR1, and ESR1 regulates the osteoblast differentiation through modulation of DLX3 expression and/or interaction with DLX3 |
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plays an essential role in the development of bones |
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is indispensable for the regulation of ion transporters and carbonic anhydrases during the maturation stage of amelogenesis, exerting a crucial regulatory function on pH oscillations during enamel mineralization |
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is a positive regulator of the aryl hydrocarbon receptor |
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