Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

PTDSS2

contributors: KTN/npt - updated : 30/10/2008

HGNC name	phosphatidylserine synthase 2
HGNC id	15463

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed PTDSS2 12 - 2473 56.1 487 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine       moderately   pancreas exocrine       highly   salivary gland       predominantly Endocrine parathyroid       moderately Nervous nerve       highly Reproductive male system testis     moderately Visual eye       highly

cell lineage
cell lines
fluid/secretion	highly in blood and lymph

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

conjugated

GlycoP

HOMOLOGY

interspecies	homolog to dog PTDSS2 (90.7 pc)
	homolog to chimpanzee PTDSS2 (97.5 pc)
	homolog to rattus Ptdss2 (91.7 pc)
	homolog to murine Ptdss2 (92.1 pc)
	homolog to chicken PTDSS2 (87.5 pc)

Homologene

FAMILY

phosphatidyl serine synthase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria
	intracellular,cytoplasm,organelle,endoplasmic reticulum
text	mitochondria-associated membrane
	multi-pass membrane protein

basic FUNCTION	catalyzing a base-exchange reaction in which the polar head group of phosphatidylethanolamine is replaced by L-serine
	acting as a CDP-diacylglycerol-serine O-phosphatidyltransferase

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

other

signaling

	phospholipid metabolism
	phosphatidylserine biosynthesis

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

inhibited by

excess phosphatidylserine

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS