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FLASH GENE
Symbol PPIH contributors: npt/ - updated : 26-07-2005
HGNC name peptidyl prolyl isomerase H (cyclophilin H)
HGNC id 14651
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
10 - 813 19.1 177 - -
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • cyclophilin domain
  • conjugated HemoP
    mono polymer heteromer , monomer , polymer
    HOMOLOGY
    interspecies homolog to C.elegans Cyp-11
    intraspecies homolog to PPIA
    Homologene
    FAMILY
  • cyclophilin family
  • CATEGORY chaperone/stress , enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,cytosolic,microsome
    intracellular,nucleus,nucleoplasm,nuclear bodies,nuclear speckles
    basic FUNCTION
  • cistransisomerization of peptidyl-prolyl bonds
  • CELLULAR PROCESS nucleotide, RNA splicing
    protein, post translation, folding
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • spliceosomal 25S (U4/U6,U5) tri-snRNP complex
  • INTERACTION
    DNA
    RNA
    small molecule cofactor, nucleotide,
  • NADPH
  • protein
  • U4/U6 specific,60kDa (PRP4)
  • flavoprotein P450 oxidoreductase (POR)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS