basic FUNCTION
| may be functioning as motors for actin-dependent organelle transport |
|
involved in transferrin trafficking |
|
play critical roles in the proper trafficking and recycling of a large number of diverse intracellular cargoes |
|
multifunctional motors recruited by a variety of Rab proteins to perform multiple tasks in a variety of distinct and overlapping recycling system |
|
with other myosin 5, are important modulator of synaptic plasticity |
|
having an important role in the transport and turnover of mRNA |
|
role for MYO5C in melanosome biogenesis and secretion |
|
MYO5A, MYO5B, and MYO5C, are involved in transport of multiple cargoes |
|
motor function of MYO5C was inhibited by its globular tail domain (GTD), and this inhibition was abolished by high Ca(2+), indicating that the tail inhibition mechanism is conserved in vertebrate MYO5A, B, C |