basic FUNCTION
| acting as a transcriptional silencer |
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being important in the regulation of the cell cycle |
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playing a critical role in oncogenic transformation and epithelial to mesenchymal transition |
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mediates cell cycle progression downstream of focal adhesion kinase (PTK2) by upregulating cyclin D1 |
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required for v-Src-induced transformation and may play a role in tumor progression of cancer |
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regulates critical cellular processes including cell cycle progression, transformation, epithelial-to-mesenchymal transition, migration and invasion by either repressing or activating target gene promoters |
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critical inducer of epithelial to mesenchymal transition and invasion |
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its overexpression induced a strong increase in MMP9 expression and activity |
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regulates critical gene transcription and cellular events associated with cancer |
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