Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TMPRSS3 | contributors: mct - updated : 18-01-2012 |
HGNC name | transmembrane protease, serine 3 |
HGNC id | 11877 |
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RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Rna function | mRNA is localized in sensory hair cells in the cochlea and the vestibule |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | fetal |
Text | cochlea, eye retina choroid, RPE, lens , anterior segment |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | monomer |
HOMOLOGY |
interspecies | ortholog to murine Mmu17 |
Homologene |
FAMILY |
CATEGORY | regulatory |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,endoplasmic reticulum | |
text | type II transmembrane serine protease |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | sensory transduction/hearing |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
inhibited by | SERPINB5 |
ASSOCIATED DISORDERS |
corresponding disease(s) | DFNB8 , DFNB10 |
related resource | Hereditary Hearing Loss Homepage |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |