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FLASH GENE
Symbol CDKL1 contributors: npt/ - updated : 26-03-2008
HGNC name cyclin-dependent kinase-like 1 (CDC2-related kinase)
HGNC id 1781
RNA
TRANSCRIPTS type messenger
text four or five isoforms in brain
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 1177 41.7 358 - -
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue   
Nervousbrain    
Reproductivefemale systemovary   
Visualeyelens   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text brain
PROTEIN
PHYSICAL PROPERTIES basic
STRUCTURE
motifs/domains
  • MAP kinase dual phosphorylation motif (Thr-Asp-Tyr)
  • HOMOLOGY
    Homologene
    FAMILY
  • protein kinase superfamily
  • CMGC Ser/Thr protein kinase family
  • CDC2/CDKX subfamily
  • CATEGORY enzyme , receptor membrane serine/threonine
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may be involved in protein amino acid phosphorylation and regulation of cell cycle
  • CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by treatment of cells with EGF
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS