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FLASH GENE
Symbol SULT1B1 contributors: mct - updated : 13-12-2017
HGNC name sulfotransferase family, cytosolic, 1B, member 1
HGNC id 17845
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 1320 - 296 - 1998 9463486
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver     Mus musculus
Nervousbrain     Mus musculus
Urinarykidneynephronrenal capsuleglomerulus  Mus musculus
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
cells
SystemCellPubmedSpeciesStageRna symbol
Urinarypodocyte Mus musculus
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer monomer
HOMOLOGY
interspecies homolog to murine Sult1d1
intraspecies homolog to SULT1
Homologene
FAMILY sulfotransferase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,Golgi
intracellular,cytoplasm,cytosolic
text
  • detected in the kidney exclusively in the Golgi apparatus of the podocyte
  • basic FUNCTION
  • catalyzing the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds
  • functional role of ST1B subfamily of sulfotransferases (STs) in xanthurenic acid sulfate formation in the body
  • may be involved in the sulfonylation of podocyte protein podocalyxin
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS