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FLASH GENE
Symbol FSCN3 contributors: - updated : 21-04-2007
HGNC name fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
HGNC id 3961
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemuterus   
 male systemtestis  specific
Urinarykidney    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/Immunedendritic cell
Reproductivespermatid
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two fascin domains
  • C terminal half actin-binding domain
  • mono polymer homomer , dimer
    HOMOLOGY
    interspecies homolog to Drosophila singed gene
    homolog to sea urchin
    Homologene
    FAMILY actin-bundling protein fascin, paralog family
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    text expressed in elongating spermatid
    basic FUNCTION
  • may function in the terminalelongation of spermatid head and çin microfilament rearrangements that accompany feryilization
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS reproduction/sex
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS