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FLASH GENE
Symbol CHST5 contributors: mct/npt - updated : 07/11/2008
HGNC name carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
HGNC id 1973
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - - 2800 - 390 - -
3 - 3265 - 411 - Kitayama (2007)
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
 intestinesmall intestine   
Hearing/Equilibriumear   highly
Nervousbrain    
Respiratoryrespiratory tracttrachea  highly
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text liver
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal cytoplasmic tail of 9AA
  • a single transmembrane domain
  • extracellular domain
  • three potential N glycosylation sites
  • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to murine Chst5
    homolog to Drosophila CG1332
    homolog to C.elegans T01H10.8
    intraspecies paralog to LSST,CHST1
    Homologene
    FAMILY
  • sulfotransferase family
  • Gal/GlcNAc/GalNAc subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • 6.0 sulfotransferase activity
  • involved in sulfation of glycoproteins and proteoglycans
  • involved in matrix morphogenesis in cornea
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    sulfation of glycoprotein and proteoglycans
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS