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FLASH GENE
Symbol CYTH4 contributors: mct/npt - updated : 02-03-2009
HGNC name cytohesin 4
HGNC id 9505
DNA
TYPE functioning gene
STRUCTURE 32.96 kb     13 Exon(s)
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
13 - 3138 45.5 394 - Beausoleil (2004)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
 thymus    
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal coiled coil domain
  • a SEC7 domain promoting guanine-nucleotide exchange on ARF1
  • a C terminal pleckstrin homology (PH) domain
  • mono polymer homomer , dimer
    HOMOLOGY
    interspecies homolog to yeast Sec7
    intraspecies homolog to PSCD1
    Homologene
    FAMILY
  • pleckstrin SeC7 domain family
  • CATEGORY signaling , transport
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • a cytosolic guanine nucleotide-exchange protein for ADF-ribosylation factors ARF1, ARF5
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule other,
  • phosphatidylinositol 3,4,5-triphosphate
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS