protein
| AIRE interacts with multiple components of the transcription complex including a novel interaction with the UBA domain protein, UBAC1 |
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UBAC1 regulates HOXA2 by promoting its relocation to the cytoplasm |
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PPP1CB and UBAC1 together inhibit the activity of HOXA2 by activating its nuclear export, but favored HOXA2 de-ubiquitination and stabilization thereby establishing a store of HOXA2 in the cytoplasm |
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UBAC1 participates to TLR3 signaling in keratinocytes, affecting also cell viability and proliferation |